Cigarette smoking reduces platelet reactivity independently of clopidogrel treatment in patients with non-ST elevation acute coronary syndromes

Cigarette smoking reduces platelet reactivity independently of clopidogrel treatment in patients with non-ST elevation acute coronary syndromes

Smokers receiving clopidogrel show a lower residual platelet reactivity than non-smokers, a phenomenon generally ascribed to smoking-induced increased production of clopidogrel active metabolite, but also associated with the high hemoglobin levels of smokers, which decreases platelet reactivity in t...

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Bibliographic Details
Main Authors: Gabriele Crimi, Alberto Somaschini, Marco Cattaneo, Dominick J Angiolillo, Federico Piscione, Tullio Palmerini, Stefano De Servi
Format: Article
Language:English
Published: Taylor & Francis Group 2018-04-01
Series:Platelets
Subjects:
high on-treatment platelet reactivity
clopidogrel
dapt
smokers paradox
vasp test
Online Access:http://dx.doi.org/10.1080/09537104.2017.1394452

Internet

http://dx.doi.org/10.1080/09537104.2017.1394452

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