Liver ERα regulates AgRP neuronal activity in the arcuate nucleus of female mice

Abstract Recent work revealed the major role played by liver Estrogen Receptor α (ERα) in the regulation of metabolic and reproductive functions. By using mutant mice with liver-specific ablation of Erα, we here demonstrate that the hepatic ERα is essential for the modulation of the activity of Agou...

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Bibliographic Details
Main Authors: Valeria Benedusi, Sara Della Torre, Nico Mitro, Donatella Caruso, Alessandra Oberto, Claire Tronel, Clara Meda, Adriana Maggi
Format: Article
Language:English
Published: Nature Portfolio 2017-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-01393-0