Cleaved CDCP1 marks the spot: a neoepitope for RAS-driven cancers

A challenge in cancer treatment is targeting cancer cells while sparing normal cells. Thus, identifying cancer-specific neoepitopes is an active research area. Neoepitopes are generated by the accumulation of mutations; however, deadly cancer types, including pancreatic cancer, have a low mutational...

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Bibliographic Details
Main Authors: Katelyn L. Donahue, Marina Pasca di Magliano
Format: Article
Language:English
Published: American Society for Clinical Investigation 2022-02-01
Series:The Journal of Clinical Investigation
Online Access:https://doi.org/10.1172/JCI157168