IL7-Fc Enhances the Efficacy of Adoptive T Cell Therapy under Lymphopenic Conditions in a Murine Melanoma Model

Adoptive cell therapy (ACT) using tumor-reactive T cells is a promising form of immunotherapy to specifically target cancer. However, the survival and functional maintenance of adoptively transferred T cells remains a challenge, ultimately limiting their efficacy. Here, we evaluated the use of recom...

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Bibliographic Details
Main Authors: Eun M. Yu, Eunjung Cho, Rohit Singh, Seon-Hee Kim, Chungyong Han, Seongeun Han, Don G. Lee, Young H. Kim, Byoung S. Kwon, Beom K. Choi
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/10/8/2018