A Bispecific Antibody to Link a TRAIL-Based Antitumor Approach to Immunotherapy

A Bispecific Antibody to Link a TRAIL-Based Antitumor Approach to Immunotherapy

T-cell-based immunotherapy strategies have profoundly improved the clinical management of several solid tumors and hematological malignancies. A recently developed and promising immunotherapy approach is to redirect polyclonal MHC-unrestricted T lymphocytes toward cancer cells by bispecific antibodi...

Full description

Bibliographic Details
Main Authors: Alessandro Satta, Giulia Grazia, Francesco Caroli, Barbara Frigerio, Massimo Di Nicola, Francesco Raspagliesi, Delia Mezzanzanica, Nadia Zaffaroni, Alessandro Massimo Gianni, Andrea Anichini, Mariangela Figini
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
bispecific antibody
TRAIL-R2
immunotherapy
T-cell retargeting
malignant ascites
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02514/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02514/full

Similar Items