Parallel learning and cognitive flexibility impairments between Fmr1 knockout mice and individuals with fragile X syndrome

Parallel learning and cognitive flexibility impairments between Fmr1 knockout mice and individuals with fragile X syndrome

IntroductionFragile X Syndrome (FXS) is a monogenic condition that leads to intellectual disability along with behavioral and learning difficulties. Among behavioral and learning difficulties, cognitive flexibility impairments are among the most commonly reported in FXS, which significantly impacts...

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Bibliographic Details
Main Authors: Lauren M. Schmitt, Anna L. Arzuaga, Ashley Dapore, Jason Duncan, Maya Patel, John R. Larson, Craig A. Erickson, John A. Sweeney, Michael E. Ragozzino
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
fragile X syndrome
FMR1
cognitive flexibility
executive function
autism
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1074682/full

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https://www.frontiersin.org/articles/10.3389/fnbeh.2022.1074682/full

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