Revisiting PI3-kinase signalling in angiogenesis

PI3Ks belong to a family of lipid kinases that comprises eight isoforms. They phosphorylate the third position of the inositol ring present in phosphatidylinositol lipids and, in turn, activate a broad range of proteins. The PI3K pathway regulates primal cellular responses, including proliferation,...

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Bibliographic Details
Main Authors: Piotr Kobialka, Mariona Graupera
Format: Article
Language:English
Published: Bioscientifica 2019-12-01
Series:Vascular Biology
Subjects:
Online Access:https://doi.org/10.1530/VB-19-0025