Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

Selective striatal neuron loss and alterations in behavior correlate with impaired striatal function in Huntington's disease transgenic rats

Huntington's disease (HD) is an inherited neurodegenerative disorder characterized by selective striatal neuron loss and motor, cognitive and affective disturbances. The present study aimed to test the hypothesis of adult-onset neuron loss in striatum and frontal cortical layer V as well as alt...

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Bibliografski detalji
Glavni autori: Orsolya Kántor, Yasin Temel, Carsten Holzmann, Kerstin Raber, Huu-Phuc Nguyen, Chunyan Cao, Hatice Özen Türkoglu, Bart P.F. Rutten, Veerle Visser-Vandewalle, Harry W.M. Steinbusch, Arjan Blokland, Hubert Korr, Olaf Riess, Stephan von Hörsten, Christoph Schmitz
Format: Članak
Jezik:English
Izdano: Elsevier 2006-06-01
Serija:Neurobiology of Disease
Teme:
Huntington's disease
Transgenic
Rat
Striatum
Cortex
Stereology
Online pristup:http://www.sciencedirect.com/science/article/pii/S0969996105003499

Internet

http://www.sciencedirect.com/science/article/pii/S0969996105003499

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