Simulated impact of RTS,S/AS01 vaccination programs in the context of changing malaria transmission.

INTRODUCTION: The RTS,S/AS01 pre-erythrocytic malaria vaccine is in phase III clinical trials. It is critical to anticipate where and how it should be implemented if trials are successful. Such planning may be complicated by changing levels of malaria transmission. METHODS/RESULTS: Computer simulati...

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Main Authors: Alan Brooks, Olivier J T Briët, Diggory Hardy, Richard Steketee, Thomas A Smith
格式: 文件
语言:English
出版: Public Library of Science (PLoS) 2012-01-01
丛编:PLoS ONE
在线阅读:http://europepmc.org/articles/PMC3295753?pdf=render