In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.

In silico ascription of gene expression differences to tumor and stromal cells in a model to study impact on breast cancer outcome.

Breast tumors consist of several different tissue components. Despite the heterogeneity, most gene expression analyses have traditionally been performed without prior microdissection of the tissue sample. Thus, the gene expression profiles obtained reflect the mRNA contribution from the various tiss...

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Bibliographic Details
Main Authors: Simen Myhre, Hayat Mohammed, Trine Tramm, Jan Alsner, Greg Finak, Morag Park, Jens Overgaard, Anne-Lise Børresen-Dale, Arnoldo Frigessi, Therese Sørlie
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2988804?pdf=render

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http://europepmc.org/articles/PMC2988804?pdf=render

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