Icaritin inhibits JAK/STAT3 signaling and growth of renal cell carcinoma.

Icaritin inhibits JAK/STAT3 signaling and growth of renal cell carcinoma.

Signal transducer and activator of transcription-3 (STAT3) is critical for cancer progression by regulating tumor cell survival, proliferation, and angiogenesis. Herein, we investigated the regulation of STAT3 activation and the therapeutic effects of Icaritin, a prenyl flavonoid derivative from Epi...

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Bibliographic Details
Main Authors: Shasha Li, Saul J Priceman, Hong Xin, Wang Zhang, Jiehui Deng, Yong Liu, Jiabin Huang, Wenshan Zhu, Mingjie Chen, Wei Hu, Xiaomin Deng, Jian Zhang, Hua Yu, Guangyuan He
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3855768?pdf=render

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http://europepmc.org/articles/PMC3855768?pdf=render

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