Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation

Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation

The abilities of cancer-associated fibroblasts (CAFs) to regulate immune responses in the context of radiotherapy remain largely unknown. This study was undertaken to determine whether ionizing radiation alters the CAF-mediated immunoregulatory effects on macrophages. CAFs were isolated from freshly...

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Bibliographic Details
Main Authors: Rodrigo Berzaghi, Muhammad Asad Ahktar, Ashraful Islam, Brede D. Pedersen, Turid Hellevik, Inigo Martinez-Zubiaurre
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:Cancers
Subjects:
cancer-associated fibroblasts
CAFs
ionizing radiation
radiotherapy
macrophages
immunoregulation
immunosuppression
Online Access:https://www.mdpi.com/2072-6694/11/5/689

Internet

https://www.mdpi.com/2072-6694/11/5/689

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