A Patient with CTLA-4 Haploinsufficiency with Multiple Autoimmune Presentations: A Case Report

A Patient with CTLA-4 Haploinsufficiency with Multiple Autoimmune Presentations: A Case Report

Increased susceptibility to autoimmunity, malignancy, and allergy in addition to recurrent infections are the main characteristics suggesting for the primary immunodeficiency diseases (PID). CTLA-4 is predominantly expressed on activated and regulatory T-cells, which can bind to CD80/CD86 molecules...

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Bibliographic Details
Main Authors: Fatemeh Zaremehrjardi, Leila Baniadam, Farhad Seif, Saba Arshi, Mohamad Hasan Bemanian, Sima Shokri, Afshin Rezaeifar, Morteza Fallahpour, Mohammad Nabavi
Format: Article
Language:English
Published: Shiraz University of Medical Sciences 2020-09-01
Series:Iranian Journal of Immunology
Subjects:
abatacept
ctla-4 deficiency
haploinsufficiency
immunodeficiency
multiple autoimmunities
Online Access:https://iji.sums.ac.ir/article_46971_5c854ff3136505f769a9e85367390b23.pdf

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https://iji.sums.ac.ir/article_46971_5c854ff3136505f769a9e85367390b23.pdf

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