A Patient with CTLA-4 Haploinsufficiency with Multiple Autoimmune Presentations: A Case Report

A Patient with CTLA-4 Haploinsufficiency with Multiple Autoimmune Presentations: A Case Report

Increased susceptibility to autoimmunity, malignancy, and allergy in addition to recurrent infections are the main characteristics suggesting for the primary immunodeficiency diseases (PID). CTLA-4 is predominantly expressed on activated and regulatory T-cells, which can bind to CD80/CD86 molecules...

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Bibliographic Details
Main Authors:	Fatemeh Zaremehrjardi, Leila Baniadam, Farhad Seif, Saba Arshi, Mohamad Hasan Bemanian, Sima Shokri, Afshin Rezaeifar, Morteza Fallahpour, Mohammad Nabavi
Format:	Article
Language:	English
Published:	Shiraz University of Medical Sciences 2020-09-01
Series:	Iranian Journal of Immunology
Subjects:	abatacept ctla-4 deficiency haploinsufficiency immunodeficiency multiple autoimmunities
Online Access:	https://iji.sums.ac.ir/article_46971_5c854ff3136505f769a9e85367390b23.pdf

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