End-of-treatment HBsAg, HBcrAg and HBV RNA predict the risk of off-treatment ALT flares in chronic hepatitis B patients

Background/Purpose(s): Since ALT flares after therapy withdrawal are associated with adverse outcomes, risk stratification is of major importance. We aimed to study whether off-treatment flares are related with virological outcomes, and if serum levels of novel biomarkers at end-of-treatment (EOT) c...

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Bibliographic Details
Main Authors: Sylvia M. Brakenhoff, Robert J. de Knegt, Margo J.H. van Campenhout, Annemiek A. van der Eijk, Willem P. Brouwer, Florian van Bömmel, André Boonstra, Bettina E. Hansen, Thomas Berg, Harry L.A. Janssen, Robert A. de Man, Milan J. Sonneveld
Format: Article
Language:English
Published: Elsevier 2023-02-01
Series:Journal of Microbiology, Immunology and Infection
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Online Access:http://www.sciencedirect.com/science/article/pii/S1684118222000937