Engineering T cell function using chimeric antigen receptors identified using a DNA library approach.

Engineering T cell function using chimeric antigen receptors identified using a DNA library approach.

Genetic engineering of cellular function holds much promise for the treatment of a variety of diseases including gene deficiencies and cancer. However, engineering the full complement of cellular functions can be a daunting genetic exercise since many molecular triggers need to be activated to achie...

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Bibliographic Details
Main Authors: Connie P M Duong, Jennifer A Westwood, Carmen S M Yong, Amanda Murphy, Christel Devaud, Liza B John, Phillip K Darcy, Michael H Kershaw
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3646939?pdf=render

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http://europepmc.org/articles/PMC3646939?pdf=render

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