Impact of GAP-43, Cx43 and actin expression on the outcome and overall survival in diffuse and anaplastic gliomas

Impact of GAP-43, Cx43 and actin expression on the outcome and overall survival in diffuse and anaplastic gliomas

Abstract Distant intercellular communication in gliomas is based on the expansion of tumor microtubuli, where actin forms cytoskeleton and GAP-43 mediates the axonal conus growth. We aimed to investigate the impact of GAP-43 and actin expression on overall survival (OS) as well as crucial prognostic...

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Bibliographic Details
Main Authors: Aleksandrs Krigers, Matthias Demetz, Patrizia Moser, Johannes Kerschbaumer, Konstantin R. Brawanski, Helga Fritsch, Claudius Thomé, Christian F. Freyschlag
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29298-1

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https://doi.org/10.1038/s41598-023-29298-1

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