CYTOR Facilitates Formation of FOSL1 Phase Separation and Super Enhancers to Drive Metastasis of Tumor Budding Cells in Head and Neck Squamous Cell Carcinoma

CYTOR Facilitates Formation of FOSL1 Phase Separation and Super Enhancers to Drive Metastasis of Tumor Budding Cells in Head and Neck Squamous Cell Carcinoma

Abstract Tumor budding (TB) is a small tumor cell cluster with highly aggressive behavior located ahead of the invasive tumor front. However, the molecular and biological characteristics of TB and the regulatory mechanisms governing TB phenotypes remain unclear. This study reveals that TB exhibits a...

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Bibliographic Details
Main Authors: Wenjin Wang, Bokai Yun, Rosalie G Hoyle, Zhikun Ma, Shadid Uz Zaman, Gan Xiong, Chen Yi, Nan Xie, Ming Zhang, Xiqiang Liu, Dipankar Bandyopadhyay, Jiong Li, Cheng Wang
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Advanced Science
Subjects:
CYTOR
FOSL1
head and neck squamous cell carcinoma
phase separation
super‐enhancer
Online Access:https://doi.org/10.1002/advs.202305002

Internet

https://doi.org/10.1002/advs.202305002

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