The RNA ligation method using modified splint DNAs significantly improves the efficiency of circular RNA synthesis

ABSTRACTCircular RNA (circRNA) is a non-coding RNA with a covalently closed loop structure and usually more stable than messenger RNA (mRNA). However, coding sequences (CDSs) following an internal ribosome entry site (IRES) in circRNAs can be translated, and this property has been recently utilized...

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Bibliographic Details
Main Authors: Yoon-Seob Kim, Do-Hyung Kim, Daegi An, Younghyun Lim, Young-Jin Seo, Hak Kyun Kim, Ho-Young Kang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Animal Cells and Systems
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/19768354.2023.2265165