The RNA ligation method using modified splint DNAs significantly improves the efficiency of circular RNA synthesis
ABSTRACTCircular RNA (circRNA) is a non-coding RNA with a covalently closed loop structure and usually more stable than messenger RNA (mRNA). However, coding sequences (CDSs) following an internal ribosome entry site (IRES) in circRNAs can be translated, and this property has been recently utilized...
Main Authors: | , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2023-12-01
|
Series: | Animal Cells and Systems |
Subjects: | |
Online Access: | https://www.tandfonline.com/doi/10.1080/19768354.2023.2265165 |