Spatial immunophenotypes predict clinical outcome in intrahepatic cholangiocarcinoma

Spatial immunophenotypes predict clinical outcome in intrahepatic cholangiocarcinoma

Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) is a severe malignant tumour that shows only modest responses to immunotherapy. We aimed to identify the spatial immunophenotypes of iCCA and delineate potential immune escape mechanisms. Method: Multiplex immunohistochemistry (mIHC)...

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Detalles Bibliográficos
Main Authors: Chunbin Zhu, Jiaqiang Ma, Kai Zhu, Lei Yu, Bohao Zheng, Dongning Rao, Shu Zhang, Liangqing Dong, Qiang Gao, Xiaoming Zhang, Diyang Xie
Formato: Artigo
Idioma:English
Publicado: Elsevier 2023-08-01
Series:JHEP Reports
Subjects:
Multiplex immunohistochemistry
Spatial immunophenotype
Immune evasion
Tumour microenvironment
Intrahepatic cholangiocarcinoma
Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2589555923000939

Internet

http://www.sciencedirect.com/science/article/pii/S2589555923000939

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