PD-L1 aptamer-functionalized degradable hafnium oxide nanoparticles for near infrared-II diagnostic imaging and radiosensitization

PD-L1 aptamer-functionalized degradable hafnium oxide nanoparticles for near infrared-II diagnostic imaging and radiosensitization

Immune checkpoint blockade is now recognized as a paradigm-shifting cancer therapeutic strategy, whereas there remains difficulty in accurately predicting immunotherapy efficacy by PD-L1 expression. In addition, radiotherapy for cancer patients faces the problem of insufficient dose of radiotherapy...

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Bibliographic Details
Main Authors: Min Wei, Xiao Shen, Xueqi Fan, Jiwei Li, Jingwen Bai
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
NIR-II fluorescence imaging
PD-L1 aptamer
checkpoint blockade immunotherapy
radiation therapy
tumor treatment
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1224339/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2023.1224339/full

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