Detection of microsatellite instability high (MSI-H) status by targeted plasma-based genotyping in metastatic breast cancer

Detection of microsatellite instability high (MSI-H) status by targeted plasma-based genotyping in metastatic breast cancer

Abstract We evaluate microsatellite instability-high (MSI-H) status with cell-free DNA (cfDNA) in metastatic breast cancer (MBC) and the association with clinico-genomic characteristics. Patients with MSI-H in cfDNA (Guardant360®, 74 gene next-generation sequencing (NGS) with MBC are identified. We...

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Bibliographic Details
Main Authors: Neelima Vidula, Andrew Lipman, Shumei Kato, Caroline Weipert, Katherine Hesler, Georges Azzi, Ahmed Elkhanany, Dejan Juric, Estelamari Rodriguez, Colleen Faulkner, Paul Makhlouf, Kristin Price, Joyce O’Shaughnessy, Aditya Bardia
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:npj Breast Cancer
Online Access:https://doi.org/10.1038/s41523-022-00490-2

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https://doi.org/10.1038/s41523-022-00490-2

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