Cellular dsRNA interactome captured by K1 antibody reveals the regulatory map of exogenous RNA sensing

Abstract RNA-binding proteins (RBPs) provide a critical post-transcriptional regulatory layer in determining RNA fate. Currently, UV crosslinking followed by oligo-dT pull-down is the gold standard in identifying the RBP repertoire of poly-adenylated RNAs, but such method is ineffective in capturing...

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Bibliographic Details
Main Authors: JinA Lim, Namseok Lee, Seonmin Ju, Jeesoo Kim, Subin Mun, Moonhyeon Jeon, Yong-ki Lee, Seok-Hoon Lee, Jayoung Ku, Sujin Kim, Sangsu Bae, Jong-Seo Kim, Yoosik Kim
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-07807-4