Unravelling the Network of Nuclear Matrix Metalloproteinases for Targeted Drug Design

Unravelling the Network of Nuclear Matrix Metalloproteinases for Targeted Drug Design

Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that are responsible for the degradation of a wide range of extracellular matrix proteins, which are involved in many cellular processes to ensure the normal development of tissues and organs. Overexpression of MMPs has been observed...

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Bibliographic Details
Main Authors: Anastasia S. Frolova, Anastasiia I. Petushkova, Vladimir A. Makarov, Surinder M. Soond, Andrey A. Zamyatnin
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:Biology
Subjects:
matrix metalloproteinase
extracellular matrix
nuclei
cancer
apoptosis
immune response
Online Access:https://www.mdpi.com/2079-7737/9/12/480

Internet

https://www.mdpi.com/2079-7737/9/12/480

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