FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells.

Forkhead box (Fox) transcription factors are important regulators of cardiovascular development and several Fox-proteins have recently been shown to modulate embryonic and post-natal angiogenesis. However, the role of the FoxP subfamily, which is highly expressed in cardiovascular tissue, has not be...

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Bibliographic Details
Main Authors: Sebastian Grundmann, Christian Lindmayer, Felix P Hans, Imo Hoefer, Thomas Helbing, Gerard Pasterkamp, Christoph Bode, Dominique de Kleijn, Martin Moser
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3759435?pdf=render