In silico exploration of phenolics as modulators of penicillin binding protein (PBP) 2× of Streptococcus pneumoniae

In silico exploration of phenolics as modulators of penicillin binding protein (PBP) 2× of Streptococcus pneumoniae

Abstract Infections caused by multidrug-resistant Streptococcus pneumoniae remain the leading cause of pneumonia-related deaths in children < 5 years globally, and mutations in penicillin-binding protein (PBP) 2 × have been identified as the major cause of resistance in the organism to beta-lacta...

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Bibliographic Details
Main Authors: Jamiu Olaseni Aribisala, Nosipho Wendy S’thebe, Saheed Sabiu
Format: Article
Language:English
Published: Nature Portfolio 2024-04-01
Series:Scientific Reports
Subjects:
Penicillin binding protein
Phenolics
Molecular dynamic simulation
Antibacterial
Streptococcus pneumoniae
Online Access:https://doi.org/10.1038/s41598-024-59489-3

Internet

https://doi.org/10.1038/s41598-024-59489-3

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