MiRNA-296-5p promotes the sensitivity of nasopharyngeal carcinoma cells to cisplatin via targeted inhibition of STAT3/KLF4 signaling axis

MiRNA-296-5p promotes the sensitivity of nasopharyngeal carcinoma cells to cisplatin via targeted inhibition of STAT3/KLF4 signaling axis

Abstract Improving drug sensitivity is an important strategy in chemotherapy of cancer and accumulating evidence indicates that miRNAs are involved in the regulation of drug sensitivity, but the specific mechanism is still unclear. Our previous study has found that miR-296-5p was significantly downr...

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Bibliographic Details
Main Authors: Hai-qing Luo, Yan Wang, Jing Ren, Quan-ying Zhang, Yan Chen, Mei-hui Chen, Ning-xin Huang, Min-hua Wu, Xu-dong Tang, Xiang-yong Li
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
miRNA-296-5p
Chemosensitivity
Nasopharyngeal carcinoma
STAT3
KLF4
Online Access:https://doi.org/10.1038/s41598-024-55123-4

Internet

https://doi.org/10.1038/s41598-024-55123-4

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