Reduced Expression of PD-1 in Circulating CD4+ and CD8+ Tregs Is an Early Feature of RRMS

Reduced Expression of PD-1 in Circulating CD4+ and CD8+ Tregs Is an Early Feature of RRMS

Altered regulatory T cell (Treg) function could contribute to MS. The expression of activating and inhibitory receptors influences the activity of Tregs. Our aim was to investigate T cell phenotypes in relapsing–remitting MS (RRMS) patients at an early phase of the disease. We examined the influence...

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Bibliographic Details
Main Authors: Maja Machcińska, Magdalena Kierasińska, Martyna Michniowska, Marta Maruszewska-Cheruiyot, Ludmiła Szewczak, Rafał Rola, Anna Karlińska, Michael Stear, Katarzyna Donskow-Łysoniewska
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:International Journal of Molecular Sciences
Subjects:
T cells
suppressive markers
cytokines
relapsing–remitting multiple sclerosis
Online Access:https://www.mdpi.com/1422-0067/23/6/3185

Internet

https://www.mdpi.com/1422-0067/23/6/3185

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