Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique

Concentration gradients of monoamines, their precursors and metabolites in serial lumbar cerebrospinal fluid of neurologically healthy patients determined with a novel LC–MS/MS technique

Abstract Background Potential biomarkers for neuropsychiatric disorders are cerebrospinal fluid (CSF) monoamines and their corresponding precursors and metabolites. During CSF sampling, CSF flows towards the lumbar sampling site from more cranial regions. To compare the results of studies in which d...

Full description

Bibliographic Details
Main Authors: Celien Tigchelaar, Willemien D. Muller, Sawal D. Atmosoerodjo, Klaas J. Wardenaar, Ido P. Kema, Anthony R. Absalom, Martijn van Faassen
Format: Article
Language:English
Published: BMC 2023-02-01
Series:Fluids and Barriers of the CNS
Subjects:
Biogenic amines
Cerebrospinal fluid (CSF)
Concentration gradients
LC–MS/MS
Online Access:https://doi.org/10.1186/s12987-023-00413-8

Internet

https://doi.org/10.1186/s12987-023-00413-8

Similar Items