Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

Integrative genomics of gene and metabolic regulation by estrogen receptors α and β, and their coregulators

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Abstract The closely related transcription factors (TFs), estrogen receptors ERα and ERβ, regulate divergent gene expression programs and proliferative outcomes in breast cancer. Utilizing breast cancer cells with ERα, ERβ, or both receptors as a model system to define the basis for differing respon...

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Bibliographic Details
Main Authors: Zeynep Madak‐Erdogan, Tze‐Howe Charn, Yan Jiang, Edison T Liu, John A Katzenellenbogen, Benita S Katzenellenbogen
Format: Article
Language:English
Published: Springer Nature 2013-06-01
Series:Molecular Systems Biology
Subjects:
coregulator usage
estrogen receptors α and β
gene regulation
metabolism
proliferation
Online Access:https://doi.org/10.1038/msb.2013.28

Internet

https://doi.org/10.1038/msb.2013.28

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