The mutational landscape of a US Midwestern breast cancer cohort reveals subtype-specific cancer drivers and prognostic markers

Abstract Background Female breast cancer remains the second leading cause of cancer-related death in the USA. The heterogeneity in the tumor morphology across the cohort and within patients can lead to unpredictable therapy resistance, metastasis, and clinical outcome. Hence, supplementing classic p...

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Bibliographic Details
Main Authors: Neetha Nanoth Vellichirammal, Yuan-De Tan, Peng Xiao, James Eudy, Oleg Shats, David Kelly, Michelle Desler, Kenneth Cowan, Chittibabu Guda
Format: Article
Language:English
Published: BMC 2023-07-01
Series:Human Genomics
Online Access:https://doi.org/10.1186/s40246-023-00511-6