IDH1 mutation decreases the invasiveness of glioma by downregulating the expression and activity of TAZ

IDH1 mutation decreases the invasiveness of glioma by downregulating the expression and activity of TAZ

Background and Aim: Gliomas carrying mutated isocitrate dehydrogenase 1 (IDH1) have an improved prognosis, but how this mutation improves survival is not known. In this study, we evaluated the correlation of expression of the gene transcriptional coactivator with PDZ-binding motif (TAZ) with IDH1 mu...

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Bibliographic Details
Main Authors: Ningning Li, Rui Zhang, Yi Sun, Chenyue Xu, Yin Wang, Ji Xiong, Qi Chen, Ying Liu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2019-01-01
Series:Glioma
Subjects:
14-3-3
2-hydroxyglutarate
astrocytoma
Hippo signaling pathway
isocitrate dehydrogenase 1 mutation
malignant grade
proliferation
transcriptional coactivator with PDZ-binding motif
Online Access:http://www.jglioma.com/article.asp?issn=2589-6113;year=2019;volume=2;issue=1;spage=37;epage=45;aulast=Li

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http://www.jglioma.com/article.asp?issn=2589-6113;year=2019;volume=2;issue=1;spage=37;epage=45;aulast=Li

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