Frequency and Significance of Ras, Tert Promoter, and Braf Mutations in Cytologically Indeterminate Thyroid Nodules: A Monocentric Case Series at a Tertiary-Level Endocrinology Unit

Frequency and Significance of Ras, Tert Promoter, and Braf Mutations in Cytologically Indeterminate Thyroid Nodules: A Monocentric Case Series at a Tertiary-Level Endocrinology Unit

PurposeThe management of thyroid nodules of indeterminate cytology is controversial. Our study aimed to establish the frequency and significance of H-,K-,N-RAS, TERT promoter, and BRAF gene mutations in thyroid nodes of indeterminate cytology and to assess their potential usefulness in clinical prac...

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Main Authors: Simona Censi, Elisabetta Cavedon, Loris Bertazza, Francesca Galuppini, Sara Watutantrige-Fernando, Paola De Lazzari, Davide Nacamulli, Gianmaria Pennelli, Ambrogio Fassina, Maurizio Iacobone, Eric Casal Ide, Federica Vianello, Susi Barollo, Caterina Mian
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-10-01
Series:Frontiers in Endocrinology
Subjects:
thyroid nodules
indeterminate thyroid cytology
TERT promoter mutations
H-,K-,N-RAS mutations
BRAF mutations
Online Access:http://journal.frontiersin.org/article/10.3389/fendo.2017.00273/full

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http://journal.frontiersin.org/article/10.3389/fendo.2017.00273/full

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