Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle.

Tyrosinase Depletion Prevents the Maturation of Melanosomes in the Mouse Hair Follicle.

The mechanisms that lead to variation in human skin and hair color are not fully understood. To better understand the molecular control of skin and hair color variation, we modulated the expression of Tyrosinase (Tyr), which controls the rate-limiting step of melanogenesis, by expressing a single-co...

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Bibliographic Details
Main Authors: Elyse K Paterson, Thomas J Fielder, Grant R MacGregor, Shosuke Ito, Kazumasa Wakamatsu, Daniel L Gillen, Victoria Eby, Raymond E Boissy, Anand K Ganesan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4664286?pdf=render

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http://europepmc.org/articles/PMC4664286?pdf=render

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