Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein

Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein

Infection of human parvovirus B19 (B19V) can cause a variety of diseases, such as hydrops fetalis, erythema infectiosum in children and acute arthropathy in women. Although B19V infection mainly occurs during childhood, about 50 % of adults are still susceptible to B19V infection. As the major repli...

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Bibliographic Details
Main Authors: Yixi Zhang, Zhiwei Shao, Yanqing Gao, Boming Fan, Jie Yang, Xi Chen, Xin Zhao, Qiyuan Shao, Weizhen Zhang, Chulei Cao, Hehua Liu, Jianhua Gan
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Human parvovirus B19
B19V
NS1 nuclease domain
Crystal structure
DNA binding
DNA cleavage
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022003828

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http://www.sciencedirect.com/science/article/pii/S2001037022003828

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