Single-cell spatial architectures associated with clinical outcome in head and neck squamous cell carcinoma

Abstract There is increasing evidence that the spatial organization of cells within the tumor-immune microenvironment (TiME) of solid tumors influences survival and response to therapy in numerous cancer types. Here, we report results and demonstrate the applicability of quantitative single-cell spa...

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Bibliographic Details
Main Authors: Katie E. Blise, Shamilene Sivagnanam, Grace L. Banik, Lisa M. Coussens, Jeremy Goecks
Format: Article
Language:English
Published: Nature Portfolio 2022-02-01
Series:npj Precision Oncology
Online Access:https://doi.org/10.1038/s41698-022-00253-z