405 Role of Glycans in Cancer Associated Fibroblast-Derived Exosome Immunoregulation

405 Role of Glycans in Cancer Associated Fibroblast-Derived Exosome Immunoregulation

OBJECTIVES/GOALS: To identify the role of sialoglycans in the mechanisms underlying cancer-associated fibroblast-derived exosomes (CAFEX) immuno-regulatory properties. The central hypothesis is that CAFEX manipulates the immune response to allow immunoevasion and glycomic approaches can identify the...

Full description

Bibliographic Details
Main Authors:	Johnathon D. Anderson, Jan Nolta, D. Gregory Farwell, Andrew Birkland, Judy Van de Water, Kermit Carraway, Carlito Lebrilla
Format:	Article
Language:	English
Published:	Cambridge University Press 2022-04-01
Series:	Journal of Clinical and Translational Science
Online Access:	https://www.cambridge.org/core/product/identifier/S2059866122002333/type/journal_article

Similar Items

Glycan Biomarkers in Cancer Diagnosis
by: Carlito B. Lebrilla
Published: (2011-12-01)

The Roles of Exosomes in Immunoregulation and Autoimmune Thyroid Diseases
by: Junli Zou, et al.
Published: (2021-11-01)

Fibroblast-Mediated Immunoregulation of Macrophage Function Is Maintained after Irradiation
by: Rodrigo Berzaghi, et al.
Published: (2019-05-01)

Pulmonary inflammation and fibroblast immunoregulation: from bench to bedside
by: Mohamed A. Ghonim, et al.
Published: (2023-09-01)

Repurposing Cationic Amphiphilic Drugs and Derivatives to Engage Lysosomal Cell Death in Cancer Treatment
by: Michelle Hu, et al.
Published: (2020-12-01)

Proteomic analysis of Bifidobacterium longum subsp. infantis reveals the metabolic insight on consumption of prebiotics and host glycans.
by: Jae-Han Kim, et al.
Published: (2013-01-01)

Lean adipose tissue macrophage derived exosome confers immunoregulation to improve wound healing in diabetes
by: Wenzheng Xia, et al.
Published: (2023-04-01)

Immunoregulation of microglia with tocotrienols
by: Tan, Shi Wei
Published: (2012)

Macrophages in immunoregulation and therapeutics
by: Shanze Chen, et al.
Published: (2023-05-01)

Immunoregulation in Fungal Diseases
by: Jonathan A. Roussey, et al.
Published: (2016-12-01)

Mesenchymal Stromal Cells Regulate Sialylations of N-Glycans, Affecting Cell Migration and Survival
by: Kayla Templeton, et al.
Published: (2021-06-01)

Cytohesin-2/ARNO: A Novel Bridge Between Cell Migration and Immunoregulation in Synovial Fibroblasts
by: Yilin Wang, et al.
Published: (2022-01-01)

Breg-Mediated Immunoregulation in the Skin
by: Elina A. Zheremyan, et al.
Published: (2024-01-01)

Immunoregulation in cancer-associated cachexia
by: Qi Wu, et al.
Published: (2024-04-01)

Immunoregulation by Helper T cell subsets
by: Robert Coffman
Published: (1988-11-01)

Editorial: Immunoregulation at mucosal surfaces
by: Javier Leceta, et al.
Published: (2022-08-01)

Immunoregulation and antidepressant effect of ketamine
by: Zhang Nan, et al.
Published: (2021-05-01)

Helminth-induced immunoregulation: an update
by: Zakzuk, Josefina
Published: (2016-04-01)

Senescence and Immunoregulation in the Tumor Microenvironment
by: Megan K. Ruhland, et al.
Published: (2021-10-01)

Immune factors and immunoregulation in tuberculosis
by: J.C. Ferraz, et al.
Published: (2006-11-01)

Luminal Conversion and Immunoregulation by Probiotics
by: Bhanu Priya Ganesh, et al.
Published: (2015-11-01)

Metabolite itaconate in host immunoregulation and defense
by: Wenchang Yang, et al.
Published: (2023-12-01)

An immunoregulator nanomedicine approach for the treatment of tuberculosis
by: Luona Yang, et al.
Published: (2023-05-01)

Immunoregulation of synovial macrophages for the treatment of osteoarthritis
by: Xu Mingze, et al.
Published: (2023-01-01)

Potential role of macrophages as immunoregulators of pregnancy
by: Abrahams Vikki M, et al.
Published: (2003-12-01)

Eicosanoids in Cancer: New Roles in Immunoregulation
by: Amber M. Johnson, et al.
Published: (2020-11-01)

Research Progress on Immunoregulation of Chemotherapeutic Agents
by: LIU Zhenghao, et al.
Published: (2022-01-01)

Negative Charge-Carrying Glycans Attached to Exosomes as Novel Liquid Biopsy Marker
by: Natalia Kosutova, et al.
Published: (2024-02-01)

Sialoglycoproteins and N-glycans from secreted exosomes of ovarian carcinoma cells.
by: Cristina Escrevente, et al.
Published: (2013-01-01)

High Mannose N-Glycans Promote Migration of Bone-Marrow-Derived Mesenchymal Stromal Cells
by: Vivian Alonso-Garcia, et al.
Published: (2020-09-01)

The Development of the Davis Food Glycopedia—A Glycan Encyclopedia of Food
by: Juan J. Castillo, et al.
Published: (2022-04-01)

Immunoregulation in normal pregnancy and pre-eclampsia: an overview.
by: Sargent, I, et al.
Published: (2007)

Immunoregulation in normal pregnancy and pre-eclampsia: an overview.
by: Sargent, I, et al.
Published: (2006)

Immunoregulation: the interplay between metabolism and redox homeostasis
by: E. Perpiñán, et al.
Published: (2023-11-01)

The Growing Relevance of Immunoregulation in Pediatric Brain Tumors
by: Viktoria Melcher, et al.
Published: (2021-11-01)

Cytokine units of immunoregulation of diabetic-associated osteoarthritis
by: V.L. Orlenko
Published: (2020-05-01)

NAD+ metabolism-based immunoregulation and therapeutic potential
by: Jiankai Fang, et al.
Published: (2023-05-01)

Immunoregulation in the testis and its implication in fertility and infections
by: Kushaan Khambata, et al.
Published: (2021-12-01)

Effects of Cadmium Exposure on the Immune System and Immunoregulation
by: Zhineng Wang, et al.
Published: (2021-07-01)

Polydopamine Nanoparticle‐Mediated Dopaminergic Immunoregulation in Colitis
by: Juanjuan Li, et al.
Published: (2022-01-01)