TREML2 Mutation Mediate Alzheimer’s Disease Risk by Altering Neuronal Degeneration

TREML2 Mutation Mediate Alzheimer’s Disease Risk by Altering Neuronal Degeneration

A coding missense mutation (rs3747742) in triggering receptor expressed on myeloid cell-like 2 (TREML2) has been recently proposed as an important protective factor against Alzheimer’s disease (AD). However, the link between TREML2 and AD pathology remains unclear. Therefore, we explored the associa...

Full description

Bibliographic Details
Main Authors: Ya-Nan Song, Jie-Qiong Li, Chen-Chen Tan, Hui-Fu Wang, Meng-Shan Tan, Xi-Peng Cao, Jin-Tai Yu, Lan Tan, the Alzheimer’s Disease Neuroimaging Initiative
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Neuroscience
Subjects:
TREML2
neurodegeneration
Alzheimer’s disease
CSF biomarkers
Alzheimer’s disease neuroimaging initiative
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2019.00455/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2019.00455/full

Similar Items