A simple and robust method for simultaneous dual-omics profiling with limited numbers of cells

Summary: Deciphering epigenetic regulation of gene expression requires measuring the epigenome and transcriptome jointly. Single-cell multi-omics technologies have been developed for concurrent profiling of chromatin accessibility and gene expression. However, multi-omics profiling of low-input bulk...

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Bibliographic Details
Main Authors: Ruifang Li, Sara A. Grimm, Paul A. Wade
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Cell Reports: Methods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667237521000862