The Influence of NAT2 Genotypes on Isoniazid Plasma Concentration of Pulmonary Tuberculosis Patients in Southern Thailand

Background Isoniazid (INH) is metabolized by polymorphic N-acetyltransferase 2 (NAT2) enzyme, which noticeably alters INH plasma concentration. We aimed to determine the distribution of NAT2 genotype in Thai tuberculosis (TB) patients and correlate their genotype with plasma INH concentrations. Meth...

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Bibliographic Details
Main Authors: Usanee Ungcharoen, Hutcha Sriplung, Surakameth Mahasirimongkol, Saranyou Chusri, Nuanjun Wichukchinda, Phongpan Mokmued, Sukanya Wattanapokayakit, Virasakdi Chongsuvivatwong
Format: Article
Language:English
Published: The Korean Academy of Tuberculosis and Respiratory Diseases 2020-12-01
Series:Tuberculosis and Respiratory Diseases
Subjects:
Online Access:http://www.e-trd.org/upload/pdf/trd-2020-0068.pdf