An efficient synthesis of N-substituted pyrroles catalyzed by MgI2 etherate

We describe a convenient and useful procedure for the synthesis of various 2,5-dimethyl-N-substituted pyrrole derivatives by the addition of 2,5-hexadione with aromatic amines, heteroaromatic amines and aliphatic amines catalyzed by MgI2 etherate (MgI2·(OEt2)n) in good to excellent yields.

Bibliographic Details
Main Authors: Zhang Yongdong, Weng Guodong, Chen Jingyan, Ma Danting, Zhang Xingxian
Format: Article
Language:English
Published: De Gruyter 2014-12-01
Series:Main Group Metal Chemistry
Subjects:
Online Access:https://doi.org/10.1515/mgmc-2014-0031