D-Serine reduces the expression of the cytopathic genotoxin colibactin

D-Serine reduces the expression of the cytopathic genotoxin colibactin

Some Escherichia coli strains harbour the pks island, a 54 kb genomic island en-coding the biosynthesis genes for a genotoxic compound named colibactin. In eukaryotic cells, colibactin can induce DNA damage, cell cycle arrest and chro-mosomal instability. Production of colibactin has been implicated...

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Bibliographic Details
Main Authors: Jennifer C. Hallam, Sofia Sandalli, Iris Floria, Natasha C. A. Turner, Min Tang-Fichaux, Eric Oswald, Nicky O’Boyle, Andrew J. Roe
Format: Article
Language:English
Published: Shared Science Publishers OG 2023-03-01
Series:Microbial Cell
Subjects:
e. coli
colibactin
expression
genotoxin
cell-cycle
Online Access:http://microbialcell.com/researcharticles/2023a-hallam-microbial-cell/

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http://microbialcell.com/researcharticles/2023a-hallam-microbial-cell/

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