Non-linear modifications enhance prediction of pathological response to pre-operative PD-1 blockade in lung cancer: A longitudinal hybrid radiological model

Non-linear modifications enhance prediction of pathological response to pre-operative PD-1 blockade in lung cancer: A longitudinal hybrid radiological model

Major pathologic remission (MPR, residual tumor <10%) is a promising clinical endpoint for prognosis analysis in patients with lung cancer receiving pre-operative PD-1 blockade therapy. Most of the current biomarkers for predicting MPR such as PD-L1 and tumor mutation burden (TMB) need to be obta...

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Bibliographic Details
Main Authors: Weiqiu Jin, Yu Tian, Wendi Xuzhang, Hongda Zhu, Ningyuan Zou, Leilei Shen, Changzi Dong, Qisheng Yang, Long Jiang, Jia Huang, Zheng Yuan, Xiaodan Ye, Qingquan Luo
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Pharmacological Research
Subjects:
Radiomics
Deep learning
Immunotherapy
Lung cancer
CT scan
Online Access:http://www.sciencedirect.com/science/article/pii/S1043661823003481

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http://www.sciencedirect.com/science/article/pii/S1043661823003481

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