Insights into the biosynthesis of septacidin l-heptosamine moiety unveils a VOC family sugar epimerase
l-Heptopyranoses are important components of bacterial polysaccharides and biological active secondary metabolites like septacidin (SEP), which represents a group of nucleoside antibiotics with antitumor, antifungal, and pain-relief activities. However, little is known about the formation mechanisms...
Main Authors: | Meng Chen, Zhengyan Guo, Jinyuan Sun, Wei Tang, Min Wang, Yue Tang, Pengwei Li, Bian Wu, Yihua Chen |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-02-01
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Series: | Acta Pharmaceutica Sinica B |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211383522002556 |
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