Composite mobile genetic elements disseminating macrolide resistance in Streptococcus pneumoniae

Composite mobile genetic elements disseminating macrolide resistance in Streptococcus pneumoniae

Macrolide resistance in Streptococcus pneumoniae emerged in the US and globally during the early 1990’s. The RNA methylase encoded by erm(B) and the macrolide efflux genes mef(E) and mel were identified as the resistance determining factors. These genes are disseminated in the pneumococcus on mobile...

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Bibliographic Details
Main Authors: Scott T Chancey, Sonia eAgrawal, Max eSchroeder, Monica M. Farley, Hervé eTettelin, David S. Stephens
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-02-01
Series:Frontiers in Microbiology
Subjects:
Macrolides
antibiotic resistance
mobile genetic elements
transposons
Integrative and conjugative elements
Streptococci pneumoniae
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00026/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00026/full

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