Drosophila nicotinic acetylcholine receptor subunits and their native interactions with insecticidal peptide toxins

Drosophila nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels that represent a target for insecticides. Peptide neurotoxins are known to block nAChRs by binding to their target subunits, however, a better understanding of this mechanism is needed for effective insecticide desig...

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Bibliographic Details
Main Authors: Dagmara Korona, Benedict Dirnberger, Carlo NG Giachello, Rayner ML Queiroz, Rebeka Popovic, Karin H Müller, David-Paul Minde, Michael J Deery, Glynnis Johnson, Lucy C Firth, Fergus G Earley, Steven Russell, Kathryn S Lilley
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/74322