Investigations on the substrate binding sites of hemolysin B, an ABC transporter, of a type 1 secretion system

Investigations on the substrate binding sites of hemolysin B, an ABC transporter, of a type 1 secretion system

The ABC transporter hemolysin B (HlyB) is the key protein of the HlyA secretion system, a paradigm of type 1 secretion systems (T1SS). T1SS catalyze the one-step substrate transport across both membranes of Gram-negative bacteria. The HlyA T1SS is composed of the ABC transporter (HlyB), the membrane...

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Bibliographic Details
Main Authors: Zohreh Pourhassan N., Eymen Hachani, Olivia Spitz, Sander H. J. Smits, Lutz Schmitt
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Microbiology
Subjects:
ABC transporter
protein secretion
putative binding pockets
substrate interaction
bacterial secretion systems
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.1055032/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.1055032/full

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