In vitro anti-Leishmania activity of triclabendazole and its synergic effect with amphotericin B

In vitro anti-Leishmania activity of triclabendazole and its synergic effect with amphotericin B

IntroductionLeishmaniasis is a neglected tropical disease, with approximately 1 million new cases and 30,000 deaths reported every year worldwide. Given the lack of adequate medication for treating leishmaniasis, drug repositioning is essential to save time and money when searching for new therapeut...

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Bibliographic Details
Main Authors: Beatriz Santana Borges, Gislayne de Paula Bueno, Fernanda Tomiotto-Pellissier, Fabiano Borges Figueiredo, Lia Carolina Soares Medeiros
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
triclabendazole
drug repurposing
Leishmaniasis
benzimidazoles
Leishmania amazonensis
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2022.1044665/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2022.1044665/full

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