p53 Represses transcription of RING finger LIM domain-binding protein RLIM through Sp1.

RLIM acts as a negative regulator of LIM-Homeodomain proteins either by recruiting Sin3A/Histone Deacetylase (HDAC) co-repressor complex or through degradation of CLIM coactivator, thus playing an important role in embryonic development. Recent studies by different research groups have shown that RL...

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Bibliographic Details
Main Authors: Xiangtao Kong, Bo Peng, Yang Yang, Pingzhao Zhang, Bo Qin, Dingding Han, Chenji Wang, Yongjun Dang, Jun O Liu, Long Yu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3641103?pdf=render