Leptin secreted by adipocytes promotes EMT transition and endometrial cancer progression via the JAK2/STAT3 signalling pathway

Leptin secreted by adipocytes promotes EMT transition and endometrial cancer progression via the JAK2/STAT3 signalling pathway

ABSTRACTBackground Endometrial cancer is a malignant tumour with a high incidence and mortality rate, and obesity is one of the most significant risk factors for the disease. However, it remains unclear whether leptin affects cell activity, proliferation, migration, invasion, and epithelial-mesenchy...

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Bibliographic Details
Main Authors: Lifan Shen, Chen Zhang, Kaiying Cui, Xin Liang, Genhai Zhu, Lan Hong
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Adipocyte
Subjects:
Leptin
endometrial cancer
EMT
cell progression
JAK2/STAT3 signalling pathway
Online Access:https://www.tandfonline.com/doi/10.1080/21623945.2023.2293273

Internet

https://www.tandfonline.com/doi/10.1080/21623945.2023.2293273

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